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Monitor Carefully (two)pentobarbital will lessen the extent or influence of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check. Powerful CYP3A4 inducers may perhaps lower suvorexant efficacy; if enhanced suvorexant dose required, will not exceed 20 mg/dayThe usage of barbiturates as sedatives from the postoperati

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